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Org 37,684
Org 37684 is a drug developed by Organon, which acts as a potent and selective agonist for the 5-HT2 receptor family, with highest affinity at 5-HT2C and lowest at 5-HT2B subtypes.〔Knight AR, Misra A, Quirk K, Benwell K, Revell D, Kennett G, Bickerdike M. Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. ''Naunyn Schmiedebergs Archives of Pharmacology''. 2004;370:114-123. PMID 15322733〕 It has anorectic effects in animal studies and has been researched as a potential weight loss drug for use in humans.〔Schreiber R, De Vry J. Role of 5-hT2C receptors in the hypophagic effect of m-CPP, ORG 37684 and CP-94,253 in the rat. ''Progress in Neuropsychopharmacology and Biological Psychiatry''. 2002 Apr;26(3):441-9. PMID 11999893〕 ==See also==
* Org 12962
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